Royal Air Force Typhoon FGR4s have operated alongside France's air force in a joint strike on an underground arms cache in Syria used by the Daesh militant organization, according to the UK Ministry of Defence.
The facility, located using intelligence, was assessed as containing munitions and bombs, the statement said, and was positioned in hills just above the ancient city of Palmyra in central Syria.
"Our aircraft utilized precision-guided Paveway IV munitions to target a series of entry passages leading to the site... initial indications indicate the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the strike conducted Saturday night and every plane involved made a safe return, the defence officials confirmed.
The British jets were backed up by a Voyager tanker plane.
Daesh - also known as ISIS - enforced militant control over parts of Syria and Iraq until 2019.
"This strike shows British leadership, and determination to operate in unison with allied nations, to eradicate any resurgence of the terrorist group and their harmful and extremist ideologies in the region," the British Defence Secretary the minister remarked.
UK warplanes have performed surveillance missions over Syrian airspace to "prevent any attempted comeback" of the group after its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I must thank every member of the UK armed forces involved in this strike for their professionalism and their valour," Healey said. "They were among thousands of British personnel deployed over Christmas and New Year. This mission, to take out militants who threaten our safety, highlights how UK forces are ready to step up, throughout the year, protecting the UK at home and powerful internationally."
During December, the United States armed forces executed what it termed a "large-scale strike" targeting Daesh sites in Syria, following an attack killed two US servicemembers and a local interpreter in Palmyra.
The UN reports Daesh still has an estimated 5,000 to 7,000 combatants in both countries.